2023 Annual Meeting
Date: October 19-21
Location: Montreal QC
October 19 & 20 – Scientific & Clinical Abstract Presentations (McGill Faculty Club)
October 21 – Symposium (The Neuro)
Registration & Banquet Tickets
Earlybird Pricing Ends Sept 1.
Preliminary Goals & Objectives
Scientific Abstract Presentations
Review of current clinical and basic science research pertaining to neuropathology with a focus on Canadian centres, but overall international participation. Also a platform for Canadian residents and trainees to present their recent work.
Diagnostic Case Presentations
Interactive discussion of rare and challenging neuropathological cases encountered by participants in their recent practice. Electronic slides and imaging results are distributed prior to meeting. Often includes case presentation by residents and illustrates advances in disease classification and diagnostic technique.
Overall learning objectives for the meeting
At the end of the meeting participants will:
- Describe recent developments in several areas of neuropathology, with particular emphasis on pediatric neuropathology.
- Discuss original research and challenging diagnostic cases with colleagues.
- Compare the practice of neuropathology on an individual and departmental level across Canadian centres.
Program
President’s Welcome Reception will be Wednesday, October 18th at the McGill Faculty Club.
0730-0800 | Registration & Breakfast (Old McGill Room) | |
0800-8:10 | Opening Remarks Robert Hammond, CANP President Peter Schutz, CANP Secretary-Treasurer |
Billiard Room |
0810-0910 | Jerzy Olszewsky Invited Lecture Olszewski, cellular snakes, and the substantia nigra. |
John Woulfe, MD, PhD University of Ottawa Ottawa, Ontario |
0910-1010 | Session 1: Scientific Abstract Presentations Developmental Neuropathology Moderator: Sumit Das |
Billiard Room |
0910-0925 | Abstract 1 Aqueductal stenosis and mesencephalosynapsis in fetal brains, part 1: classification, and morphology |
Dr. Yael Fisher |
0925-0940 | Abstract 2 Aqueductal stenosis and mesencephalosynapsis in fetal brains, part 2: associations |
Dr. Yael Fisher |
0940-0955 | Abstract 3 A novel association: distal arthrogryposis, KIF21A and fetal neuroaxonal dystrophy |
Dr. Leslie Hamilton |
0955-1010 | Abstract 4 Polymicrogyria through a tensegrity lens |
Dr. Robert Hammond |
1010-1030 | Break | Old McGill Room |
1030-1200 | Session 2: Scientific Abstract Presentations Neurodegenerative and Muscle Pathology Moderator: Dr. Veronica Hirsch-Reinshagen |
Billiard Room |
1030-1100 | Special Lecture TMEM106B in neurodegenerative disease and aging |
Ian Mackenzie, MD University of British Columbia Vancouver, British Columbia |
1100-1115 | Abstract 5 Imaging axonal pathology in the retina as a potential non-invasive biomarker for amyotrophic lateral sclerosis |
Farbod Khorrami |
1115-1130 | Abstract 6 Progressive Supranuclear Palsy: a Novel Phenotype of Germline SQSTM1 (p62) Mutation |
Dr. Madison Gray |
1130-1145 | Abstract 7 A 108 year old brain with near normal cognition |
Dr. David Munoz |
1145-1200 | Abstract 8 Cellular activation patterns of CD10+ fibro-adipogenic progenitors across acquired disease states in human skeletal muscle biopsies |
Dr. Peter Schutz |
1200-1315 | Lunch (Please make own arrangements, lunch not served) We suggest: Timeout Market, 705 rue Sainte-Catherine Ouest, Montreal. |
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1315-1500 | Session 3: Scientific Abstract Presentations Trauma, vascular, and other Moderator: Kristopher D. Langdon, MD PhD FRCPC |
Billiard Room |
1315-1330 | Abstract 9 Assessment challenges and headaches in the implementation of Competence By Design (CBD): The experience in a Diagnostic and Molecular Pathology residency program |
Dr. Hao Li |
1330-1345 | Abstract 10 Isolated small vessel inflammation in temporal artery biopsies: small red flags |
Dr. Shervin Pejhan |
1345-1400 | Abstract 11 The International Spinal Cord Injury Biobank: Neuropathological contributions to global translational research in traumatic spinal cord injury |
Dr. Veronica Hirch-Reinshagen |
1400-1415 | Abstract 12 Death and the MAiD at the Calgary Brain Bank |
Dr. Jeffrey Joseph |
1415-1430 | Abstract 13 WITHDRAWN Blunt truths: Innovations in identifying neck injuries from infant head trauma |
Dr. Evan Matshes |
1430-1445 | Abstract 14 WITHDRAWN Eyes or lies? Navigating ocular pathology controversies in infant head trauma |
Dr. Evan Matshes |
1415-1430 | Abstract 15 Pathology of the vertebral artery in medicolegal autopsies |
Dr. Fabio Tironi |
1530-1930 | RCPSC NP Specialty Training Committee Meeting | |
1530-1800 |
NEW – Neuropathology Residents’ Workshop: Molecular Investigations for CNS tumours. Moderators: Learning Objectives At the end of this workshop, participants will be able to:
Target Audience: Residents, fellows, medical students CanMeds roles: Medical expert, Collaborator, Leader, Health Advocate, Scholar |
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1530-1550 | Dr. Adrian Levine (Neuropathologist, Hospital for Sick Children) Molecular testing capabilities for CNS tumours and approach at SickKids |
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1550-1610 | Dr. Romain Cayrol (Neuropathologist, CHU Montreal) A practical approach to the molecular diagnosis of CNS tumors |
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1610-1630 | Dr. Sébastien Perreault (Neuro-Oncologist, CHU Ste-Justine) The Clinical Implications of Molecular Testing for CNS Tumours, with a focus on Pediatric Low Grade Glioma |
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1630-1645 | Break | |
1645-1745 | Case Panel Discussion – CLICK HERE to view the images for review |
0730-0815 | Breakfast and Registration (Old McGill Room) | |
0815-0930 | Session 4: Scientific Abstracts Presentations Tumour Moderator: Jason Karamchandani, MD |
Billiard Room |
0815-0830 | Abstract 16 Study of gamma-aminobutyric acid and glutamate signaling pathways in glioblastoma |
Dr. Raul Cotau |
0830-0845 | Abstract 17 Using molecular and immunohistochemical features to predict outcomes in grade 3 meningiomas |
Dr. Karina Chornenka Martin |
0845-0900 | Abstract 18 Pediatric-type gliomas in adults: pathologic and molecular features |
Dr. Andrew Gao |
0900-0915 | Abstract 19 Extra-pineal papillary tumor of the pineal region (PTPR) masquarading as a subependymal giant cell tumor (SEGA) |
Dr. Kenrick Wysong |
0915-0930 | Abstract 20 Ethical considerations in the use of DNA methylation profiling for tumor diagnostics |
Dr. Kyle Conway |
0930-1000 | Break | Old McGill Room |
1000-1130 |
Neuropathology in Practice Forum: Molecular Testing of Brain Tumors
At the end of the session, participants will be able to:
Conflict of Interest statements: Dr. Del Bigio has a relationship with a for-profit and/or a not-for-profit organization to disclose: Cambridge University Press – book sales royalties (Perinatal Neuropathology) All other speakers have nothing to disclose. |
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1130-1245 | Lunch (Please make own arrangements, lunch not served) We suggest: Timeout Market, 705 rue Sainte-Catherine Ouest, Montreal. |
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1245-1415 | Diagnostic Cases – Session I Moderator: Dr. Andrew Gao |
Billiard Room |
1246-1257 | Case #1 | Dr. Romain Cayrol |
1259-1310 | Case #2 | Dr. Assem Alrumeh |
1312-1323 | Case #3 | Dr. Alexander Easton |
1325-1336 | Case #4 | Dr. Karina Chornenka |
1338-1349 | Case #5 | Dr. Claire Coire |
1351-1402 | Case #6 | Dr. Karam Han |
1404-1415 | Case #7 | Dr. Arnulf Koeppen |
1415-1430 | Break | Old McGill Room |
1430-1600 | Diagnostic Cases – Session II Moderator: Dr. Andrew Gao |
Billiard Room |
1431-1442 | Case #8 | Dr. Christother Newell |
1444-1455 | Case #9 | Dr. Shane Eaton |
1457-1508 | Case #10 | Dr. Abdelhakim Khellaf |
1510-1521 | Case #11 | Dr. Benjamin Ellezam |
1523-1534 | Case #12 | Dr. Gabrielle Yeaney |
1536-1547 | Case #13 | Dr. John P. Rossiter |
1549-1600 | Case #14 | Dr. Jacob A. Houpt |
1700-1800 | Maude Abbott Medical Museum – Osler Collection Dr. Richard Fraser – guided tour |
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1800-1830 | Bus transport from Maude Abbott Medical Museum to L’Auberge Saint-Gabriel | |
1830-2130 | CANP ANNUAL BANQUET – L’AUBERG SAINT-GABRIEL | |
2130 | Bus transport from L’Auberg Saint-Gabriel to OMNI Hotel | |
Presidential Symposium: Pediatric Neuropathology Moderators: |
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0700-0800 | Bagel breakfast and Registration | |
0750-0800 | Welcome and Pre-Test | |
0800-0850 | Invited Lecture Topic: Epidemiology and clinical aspects of cerebral palsy in Canada |
Maryam Oskoui, MD McGill University Montreal, Quebec |
0850-0940 | Gordon Mathieson Lecture Topic: In utero infections and their effects on the developing brain. |
Marc Del Bigio, MD, PhD University of Manitoba Winnipeg, Manitoba |
0940-1000 | Break | |
1000-1050 | David Robertson Lecture Title: Models And Mechanisms Of Cerebral Cortical Expansion And Folding |
David van Essen, PhD Washington University School of Medicine St. Louis, Missouri |
1050-1140 | Invited Lecture Title: Cerebral Gray Matter Injuries in Infants with Intraventricular Hemorrhage |
Praveen Ballabh, MD Albert Einstein College of Medicine New York, New York. |
1140-1230 | Invited Lecture Title: Cns Manifestations Of Dicer1 Tumor Predisposition Syndrome |
William Foulkes, MBBS, PhD McGill University Montreal, Quebec |
1230-1245 | Post-Test; Resident prizes; Closing remarks, Adjournment Moderator: Robert Hammond, Peter Schutz |
Printed programs will not be available on site. If you would like a printed copy of the program, abstracts and diagnostic cases, please download and print them below.
Mary Tom Award
Best Clinical Paper
Dr. Karina Chornenka Martin
Using molecular and immunohistochemical features to predict outcomes in grade 3 meningiomas
Morrison H. Finlayson Award
Best Basic Science
Dr. Raul Cotau
Study of gamma-aminobutyric acid and glutamate signaling pathways in glioblastoma
Invited Lecturers
Details on our invited lecturers can be viewed here.
Scientific Abstracts
Abstract #1
Abstract 1- 1010-1025 Category: Clinical At the end of the session, participants will be able to: Describe the morphologic spectrum of aqueductal stenosis Define mesencephalosynapsis and its association with aqueductal lesions and other CNS malformations. COI...
Abstract #2
Abstract 2- 1025-1040 Category: Clinical At the end of the session, participants will be able to: Describe the spectrum of aqueductal stenosis in distinct brain anomalies. Review the presence of the median dorsal glial septum in primary and secondary brain anomalies....
Abstract #3
Abstract 3- 1040-1055 Category: Clinical At the end of the session, participants will be able to: Describe the biologic roles of KIF21A and their linkage to human disease Discuss the association between KIF21A and fetal arthrogryposis Recognize the neuropathological...
Abstract #4
Abstract 4- 1055-1010 Category: Clinical At the end of the session, participants will be able to: To review the pathological features of polymicrogyria, particularly in the setting of congenital CMV encephalitis (CMVE) To consider how the injuries in congenital CMVE...
Abstract #5
Abstract 5- 1100-1115 Category: Basic Science At the end of the session, participants will be able to: Understand the axonal pathology in the retina in ALS. Describe the potential use of different non-invasive eye imaging modalities for assessing ocular biomarkers of...
Abstract #6
Abstract 6- 1115-1130 Category: Clinical At the end of the session, participants will be able to: Appreciate the genetic landscape of familial neurodegenerative disease COI Disclosure: None to disclose.Presenter Madison Gray is currently a PGY5 resident in...
Abstract #7
Abstract 7- 1130-1145 Category: Clinical At the end of the session, participants will be able to: To recognize brain histological changes in the oldest-old To become aware of brain resilience in the oldest-old To explore possible relationships between TDP-43 and...
Abstract #8
Abstract 8- 1145-1200 Category: Basic Science At the end of the session, participants will be able to: Describe the histological appearance and pathological reaction patterns of fibro adipogenic progenitors upon CD10 immunohistochemical staining. List patterns of...
Abstract #9
Abstract 9- 1315-1330 Category: Clinical At the end of the session, participants will be able to: List potential challenges with respect to assessment in Competency by Design (CBD) in Neuropathology residency Describe the reasons for such challenges Propose possible...
Abstract #10
Abstract 10- 1330-1345 Category: Clinical At the end of the session, participants will be able to: Gaining insight into the various subtleties of pathologic features observed in temporal artery biopsies. Understanding the possible clinical and prognostic significance...
Abstract #11
Abstract 11- 1345-1400 Category: Basic Science At the end of the session, participants will be able to: Understand the need for human biospecimens in translational traumatic SCI research. To introduce the International Spinal Cord Injury Biobank, a Canadian resource...
Abstract #12
Abstract 12- 1400-1415 Category: Clinical At the end of the session, participants will be able to: Learn important quality parameters in brain bank tissue Understand that MAiD patients represent an important source of autopsy brain tissue COI Disclosure: None to...
Abstract #13
Abstract 13- 1415-1430 Category: Clinical At the end of the session, participants will be able to: Understand the Connection between Blunt Head Trauma and Neck Injuries in Infants Evaluate Traditional and Advanced Spine Examination Techniques Comprehend the...
Abstract #14
Abstract 14- 1430-1445 Category: Clinical At the end of the session, participants will be able to: Understand the spectrum of ocular pathologies linked to pediatric head trauma Review the underlying theories of ocular pathology frequently documented in infant head...
Abstract #15
Abstract 15- 1445-1500 Category: Clinical At the end of the session, participants will be able to: Understand segmental vulnerability of the vertebral artery to injury and disease under a forensicperspective. Analyze the role of peripheral arteries examination and...
Travel Bursaries
The Canadian Association of Neuropathologists Endowment Trust has established a grant program to assist residents in Neuropathology or other accredited Laboratory Medicine Residency training programs, as well as undergraduate and postgraduate students in Neuroscience, to attend the Annual Meeting of the Association for the purpose of presenting a diagnostic case or delivering an abstract.
The total amount in this award program will be a maximum of $3,000 per year, and the value of each award will be this sum divided by the number of eligible applicants, up to a maximum of $750 per applicant.
This program is intended to supplement existing funding and will only cover expenses not otherwise or only partially reimbursed. Payment of the award will normally be contingent upon submission of original receipts.
To apply, submit a letter from a co-author who is a Member in good standing of the Association describing the nature of the applicant’s participation in the presentation to the Secretary-Treasurer of the CANP.
Deadline to submit is two weeks after the close of the Annual Meeting each year.
Diagnostic Case Studies
Case #1
Presenter Romain CayrolAuthors Romain Cayrol1, Stephanie Wang2, Patrick Benoit3, Abdelhakim Khellaf1, Michael Desjardins3, Kristof Nelson2, Me-Linh Luong3 1Division of Pathology, Department of Clinical Laboratory Medicine, Centre Hospitalier de l’Université de...
Case #2
Presenter Assem S. AlrumehAuthors Assem S. Alrumeh1,2, Cynthia Hawkins1,3, Gelareh Zadeh4, Phedias Diamandis1,2, Andrew F. Gao1,2 1Dept. of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada 2Laboratory Medicine Program, University Health...
Case #3
Presenter Alexander S. EastonAuthors Abigale D. Maclellan1, Gwynedd E. Pickett1,2, Alexander S. Easton1,3 1Faculty of Medicine, 2Division of Neurosurgery, 3Department of Pathology, Dalhousie University, Halifax, Nova Scotia, CanadaClinical Summary This 63 year old...
Case #4
Presenter Karina Chornenka MartinAuthors Karina Chornenka Martin1, Peter W. Schutz1 Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, CanadaClinical Summary A 33-year-old female with past medical history of...
Case #5
Presenter Claire CoireAuthors Claire I. Coire1, David G. Munoz2, Mihaly Kis3 1 Trillium Health Partners, Mississauga Hospital, and Laboratory Medicine and Pathobiology, University of Toronto, Toronto ON Canada. 2 Unity Health Toronto, St. Michael’s Hospital and...
Case #6
Presenter Karam HanAuthors Karam Han 1, Harry V. Vinters 2,3, Shino D. Magaki 2 1 School of Medicine and Public Health, Department of Pathology, University of Wisconsin, Madison, WI 53792, USA 2 Department of Pathology and Laboratory Medicine, David Geffen School of...
Case #7
Presenter Arnulf KoeppenAuthors Arnulf H. Koeppen Research Service, VA Medical Center, Albany, NY12208Clinical Summary A forensic pathologist forwarded the brain of a 56-year-old man who ran a rural tavern in upstate New York. The neuropathological interest arose from...
Case #8
Presenter Christopher NewellAuthors Christopher Newell 1, Katayoon Jafari 1, Kristopher D. Langdon 1, Denise Ng 1 1 Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, AB, CanadaClinical Summary A 26-year-old male presented in January 2020...
Case #9
Presenter Shane EatonAuthors Shane Eaton1, Liesly Lee2, Zachary Feilchenfeld3, Chris Heyn4, Cynthia Hawkins1,5, Julia L. Keith1,6 1 Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada 2 Department of Medicine, Division of Neurology,...
Case #10
Presenter Abdelhakim KhellafAuthors Romain Cayrol1, Abdelhakim Khellaf1, André Lamettti2, 3, Marie-Christine Guiot2, 3, 4, Jason Karamchandani2, 3, 4, José Ferreira5 1Division of Pathology, Department of Clinical Laboratory Medicine, Centre Hospitalier de l’Université...
Case #11
Presenter Benjamin EllezamAuthors Benjamin Ellezam1, Nathalie Langlais2 1Division of Pathology, CHU Sainte-Justine, Montréal, QC, Canada 2Division of Rheumatology, CHR de Lanaudière, St-Charles-Borromée, QC, CanadaClinical Summary A 48-year-old male with a history of...
Case #12
Presenter Gabrielle A. YeaneyAuthors Gabrielle A. Yeaney Division of Neuropathology, Pathology and Lab Medicine Institute, Cleveland Clinic, Cleveland, OHClinical Summary A 58-year-old man with history of a lung mass now has a right cerebellar tumor on imaging. The...