2023 Annual Meeting
Date: October 19-21
Location: Montreal QC
October 19 & 20 – Scientific & Clinical Abstract Presentations (McGill Faculty Club)
October 21 – Symposium (The Neuro)
Registration & Banquet Tickets
Earlybird Pricing Ends Sept 1.
Preliminary Goals & Objectives
Scientific Abstract Presentations
Review of current clinical and basic science research pertaining to neuropathology with a focus on Canadian centres, but overall international participation. Also a platform for Canadian residents and trainees to present their recent work.
Diagnostic Case Presentations
Interactive discussion of rare and challenging neuropathological cases encountered by participants in their recent practice. Electronic slides and imaging results are distributed prior to meeting. Often includes case presentation by residents and illustrates advances in disease classification and diagnostic technique.
Overall learning objectives for the meeting
At the end of the meeting participants will:
- Describe recent developments in several areas of neuropathology, with particular emphasis on pediatric neuropathology.
- Discuss original research and challenging diagnostic cases with colleagues.
- Compare the practice of neuropathology on an individual and departmental level across Canadian centres.
Program
President’s Welcome Reception will be Wednesday, October 18th at the McGill Faculty Club.
| 0730-0800 | Registration & Breakfast (Old McGill Room) | |
| 0800-8:10 | Opening Remarks Robert Hammond, CANP President Peter Schutz, CANP Secretary-Treasurer |
Billiard Room |
| 0810-0910 | Jerzy Olszewsky Invited Lecture Olszewski, cellular snakes, and the substantia nigra. |
John Woulfe, MD, PhD University of Ottawa Ottawa, Ontario |
| 0910-1010 | Session 1: Scientific Abstract Presentations Developmental Neuropathology Moderator: Sumit Das |
Billiard Room |
| 0910-0925 | Abstract 1 Aqueductal stenosis and mesencephalosynapsis in fetal brains, part 1: classification, and morphology |
Dr. Yael Fisher |
| 0925-0940 | Abstract 2 Aqueductal stenosis and mesencephalosynapsis in fetal brains, part 2: associations |
Dr. Yael Fisher |
| 0940-0955 | Abstract 3 A novel association: distal arthrogryposis, KIF21A and fetal neuroaxonal dystrophy |
Dr. Leslie Hamilton |
| 0955-1010 | Abstract 4 Polymicrogyria through a tensegrity lens |
Dr. Robert Hammond |
| 1010-1030 | Break | Old McGill Room |
| 1030-1200 | Session 2: Scientific Abstract Presentations Neurodegenerative and Muscle Pathology Moderator: Dr. Veronica Hirsch-Reinshagen |
Billiard Room |
| 1030-1100 | Special Lecture TMEM106B in neurodegenerative disease and aging |
Ian Mackenzie, MD University of British Columbia Vancouver, British Columbia |
| 1100-1115 | Abstract 5 Imaging axonal pathology in the retina as a potential non-invasive biomarker for amyotrophic lateral sclerosis |
Farbod Khorrami |
| 1115-1130 | Abstract 6 Progressive Supranuclear Palsy: a Novel Phenotype of Germline SQSTM1 (p62) Mutation |
Dr. Madison Gray |
| 1130-1145 | Abstract 7 A 108 year old brain with near normal cognition |
Dr. David Munoz |
| 1145-1200 | Abstract 8 Cellular activation patterns of CD10+ fibro-adipogenic progenitors across acquired disease states in human skeletal muscle biopsies |
Dr. Peter Schutz |
| 1200-1315 | Lunch (Please make own arrangements, lunch not served) We suggest: Timeout Market, 705 rue Sainte-Catherine Ouest, Montreal. |
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| 1315-1500 | Session 3: Scientific Abstract Presentations Trauma, vascular, and other Moderator: Kristopher D. Langdon, MD PhD FRCPC |
Billiard Room |
| 1315-1330 | Abstract 9 Assessment challenges and headaches in the implementation of Competence By Design (CBD): The experience in a Diagnostic and Molecular Pathology residency program |
Dr. Hao Li |
| 1330-1345 | Abstract 10 Isolated small vessel inflammation in temporal artery biopsies: small red flags |
Dr. Shervin Pejhan |
| 1345-1400 | Abstract 11 The International Spinal Cord Injury Biobank: Neuropathological contributions to global translational research in traumatic spinal cord injury |
Dr. Veronica Hirch-Reinshagen |
| 1400-1415 | Abstract 12 Death and the MAiD at the Calgary Brain Bank |
Dr. Jeffrey Joseph |
| 1415-1430 | Abstract 13 WITHDRAWN Blunt truths: Innovations in identifying neck injuries from infant head trauma |
Dr. Evan Matshes |
| 1430-1445 | Abstract 14 WITHDRAWN Eyes or lies? Navigating ocular pathology controversies in infant head trauma |
Dr. Evan Matshes |
| 1415-1430 | Abstract 15 Pathology of the vertebral artery in medicolegal autopsies |
Dr. Fabio Tironi |
| 1530-1930 | RCPSC NP Specialty Training Committee Meeting | |
| 1530-1800 |
NEW – Neuropathology Residents’ Workshop: Molecular Investigations for CNS tumours. Moderators: Learning Objectives At the end of this workshop, participants will be able to:
Target Audience: Residents, fellows, medical students CanMeds roles: Medical expert, Collaborator, Leader, Health Advocate, Scholar |
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| 1530-1550 | Dr. Adrian Levine (Neuropathologist, Hospital for Sick Children) Molecular testing capabilities for CNS tumours and approach at SickKids |
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| 1550-1610 | Dr. Romain Cayrol (Neuropathologist, CHU Montreal) A practical approach to the molecular diagnosis of CNS tumors |
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| 1610-1630 | Dr. Sébastien Perreault (Neuro-Oncologist, CHU Ste-Justine) The Clinical Implications of Molecular Testing for CNS Tumours, with a focus on Pediatric Low Grade Glioma |
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| 1630-1645 | Break | |
| 1645-1745 | Case Panel Discussion – CLICK HERE to view the images for review | |
| 0730-0815 | Breakfast and Registration (Old McGill Room) | |
| 0815-0930 | Session 4: Scientific Abstracts Presentations Tumour Moderator: Jason Karamchandani, MD |
Billiard Room |
| 0815-0830 | Abstract 16 Study of gamma-aminobutyric acid and glutamate signaling pathways in glioblastoma |
Dr. Raul Cotau |
| 0830-0845 | Abstract 17 Using molecular and immunohistochemical features to predict outcomes in grade 3 meningiomas |
Dr. Karina Chornenka Martin |
| 0845-0900 | Abstract 18 Pediatric-type gliomas in adults: pathologic and molecular features |
Dr. Andrew Gao |
| 0900-0915 | Abstract 19 Extra-pineal papillary tumor of the pineal region (PTPR) masquarading as a subependymal giant cell tumor (SEGA) |
Dr. Kenrick Wysong |
| 0915-0930 | Abstract 20 Ethical considerations in the use of DNA methylation profiling for tumor diagnostics |
Dr. Kyle Conway |
| 0930-1000 | Break | Old McGill Room |
| 1000-1130 |
Neuropathology in Practice Forum: Molecular Testing of Brain Tumors
At the end of the session, participants will be able to:
Conflict of Interest statements: Dr. Del Bigio has a relationship with a for-profit and/or a not-for-profit organization to disclose: Cambridge University Press – book sales royalties (Perinatal Neuropathology) All other speakers have nothing to disclose. |
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| 1130-1245 | Lunch (Please make own arrangements, lunch not served) We suggest: Timeout Market, 705 rue Sainte-Catherine Ouest, Montreal. |
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| 1245-1415 | Diagnostic Cases – Session I Moderator: Dr. Andrew Gao |
Billiard Room |
| 1246-1257 | Case #1 | Dr. Romain Cayrol |
| 1259-1310 | Case #2 | Dr. Assem Alrumeh |
| 1312-1323 | Case #3 | Dr. Alexander Easton |
| 1325-1336 | Case #4 | Dr. Karina Chornenka |
| 1338-1349 | Case #5 | Dr. Claire Coire |
| 1351-1402 | Case #6 | Dr. Karam Han |
| 1404-1415 | Case #7 | Dr. Arnulf Koeppen |
| 1415-1430 | Break | Old McGill Room |
| 1430-1600 | Diagnostic Cases – Session II Moderator: Dr. Andrew Gao |
Billiard Room |
| 1431-1442 | Case #8 | Dr. Christother Newell |
| 1444-1455 | Case #9 | Dr. Shane Eaton |
| 1457-1508 | Case #10 | Dr. Abdelhakim Khellaf |
| 1510-1521 | Case #11 | Dr. Benjamin Ellezam |
| 1523-1534 | Case #12 | Dr. Gabrielle Yeaney |
| 1536-1547 | Case #13 | Dr. John P. Rossiter |
| 1549-1600 | Case #14 | Dr. Jacob A. Houpt |
| 1700-1800 | Maude Abbott Medical Museum – Osler Collection Dr. Richard Fraser – guided tour |
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| 1800-1830 | Bus transport from Maude Abbott Medical Museum to L’Auberge Saint-Gabriel | |
| 1830-2130 | CANP ANNUAL BANQUET – L’AUBERG SAINT-GABRIEL | |
| 2130 | Bus transport from L’Auberg Saint-Gabriel to OMNI Hotel | |
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Presidential Symposium: Pediatric Neuropathology Moderators: |
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| 0700-0800 | Bagel breakfast and Registration | |
| 0750-0800 | Welcome and Pre-Test | |
| 0800-0850 | Invited Lecture Topic: Epidemiology and clinical aspects of cerebral palsy in Canada |
Maryam Oskoui, MD McGill University Montreal, Quebec |
| 0850-0940 | Gordon Mathieson Lecture Topic: In utero infections and their effects on the developing brain. |
Marc Del Bigio, MD, PhD University of Manitoba Winnipeg, Manitoba |
| 0940-1000 | Break | |
| 1000-1050 | David Robertson Lecture Title: Models And Mechanisms Of Cerebral Cortical Expansion And Folding |
David van Essen, PhD Washington University School of Medicine St. Louis, Missouri |
| 1050-1140 | Invited Lecture Title: Cerebral Gray Matter Injuries in Infants with Intraventricular Hemorrhage |
Praveen Ballabh, MD Albert Einstein College of Medicine New York, New York. |
| 1140-1230 | Invited Lecture Title: Cns Manifestations Of Dicer1 Tumor Predisposition Syndrome |
William Foulkes, MBBS, PhD McGill University Montreal, Quebec |
| 1230-1245 | Post-Test; Resident prizes; Closing remarks, Adjournment Moderator: Robert Hammond, Peter Schutz |
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Printed programs will not be available on site. If you would like a printed copy of the program, abstracts and diagnostic cases, please download and print them below.
Mary Tom Award
Best Clinical Paper
Dr. Karina Chornenka Martin
Using molecular and immunohistochemical features to predict outcomes in grade 3 meningiomas
Morrison H. Finlayson Award
Best Basic Science
Dr. Raul Cotau
Study of gamma-aminobutyric acid and glutamate signaling pathways in glioblastoma
Invited Lecturers
Details on our invited lecturers can be viewed here.
Scientific Abstracts
Abstract #16
Abstract 16- 0815-0830 Category: Basic Science At the end of the session, participants will be able to: Discuss the role of neurotransmission molecules regarding glioblastoma development and survival. Recognize informatic tools utilized for both cellular...
Abstract #17
Abstract 17- 0830-0845 Category: Clinical At the end of the session, participants will be able to: Discuss molecular alterations that impact survival in grade 3 meningiomas. Illustrate immunohistochemical stains that may be used as potential surrogate markers for...
Abstract #18
Abstract 18- 0845-0900 Category: Clinical At the end of the session, participants will be able to: Understand the prevalence of pediatric-type alterations in gliomas in adults Appreciate the molecular and pathologic features of pediatric-type gliomas in adults...
Abstract #19
Abstract 19- 0900-0915 Category: Clinical At the end of the session, participants will be able to: Identify the diagnostic features of papillary tumor of the pineal region. Identify the diagnostic features of subependymal giant cell astrocytoma. Explain the utility of...
Abstract #20
Abstract 20- 0915-0930 Category: Clinical At the end of the session,participants will be able to: Apply traditional principles of biomedical ethics to the implementation and application of DNA methylation profiling for tumor diagnostics. Distinguish the ethical...
Travel Bursaries
The Canadian Association of Neuropathologists Endowment Trust has established a grant program to assist residents in Neuropathology or other accredited Laboratory Medicine Residency training programs, as well as undergraduate and postgraduate students in Neuroscience, to attend the Annual Meeting of the Association for the purpose of presenting a diagnostic case or delivering an abstract.
The total amount in this award program will be a maximum of $3,000 per year, and the value of each award will be this sum divided by the number of eligible applicants, up to a maximum of $750 per applicant.
This program is intended to supplement existing funding and will only cover expenses not otherwise or only partially reimbursed. Payment of the award will normally be contingent upon submission of original receipts.
To apply, submit a letter from a co-author who is a Member in good standing of the Association describing the nature of the applicant’s participation in the presentation to the Secretary-Treasurer of the CANP.
Deadline to submit is two weeks after the close of the Annual Meeting each year.
Diagnostic Case Studies
Case #13
Presenter John P. RossiterAuthors John P. Rossiter, Minqi Xu, Sandip SenGupta Department of Pathology and Molecular Medicine, Queen’s University, Kingston, ON, Canada.Clinical Summary A 29 year old man died suddenly and unexpectedly. Following detailed postmortem...
Case #14
Presenter Jacob A. HouptAuthors Jacob A. Houpt 1, Tommaso Romagnoli 1, Christopher Howlett 1, Shayna Zelcer 2, Lee-Cyn Ang1 1 Department of Pathology and Laboratory Medicine, London Health Sciences Centre, London, ON, Canada2 Division of Haematology/Oncology, Western...