Presenter

Stephanie R. Beldick

Bio

Dr. Stephanie Beldick is a neuropathology resident at Western University in London, Ontario. She completed her Master’s at the University of Toronto in neuroscience, followed by medical school and two years of postgraduate ophthalmology training in the United States prior to joining the field of neuropathology. Her research interests include basic science and clinical investigations of neurodevelopmental processes.

Authors and Affiliations

Stephanie R. Beldick1, Prateek Malik2, Cynthia Hawkins3, Pat Allevato4, Qi Zhang1, Lee-Cyn Ang1, & Robert Hammond1
1 Department of Pathology and Laboratory Medicine, London Health Sciences Centre, London, ON
2 Department of Medical Imaging, London Health Sciences Centre, London, ON
3 Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON
4 Department of Pathology, Windsor Regional Hospital, Windsor, ON

Conflict of Interest

I do not have a relationship with a for-profit and/or a not-for-profit organization to disclose.

Clinical Summary

21-year-old woman with a history of epilepsy since age two and scoliosis status-post surgery presented to Windsor Regional Hospital (WRH) with symptoms of headache and double vision for one month. Imaging revealed intraventricular tumours (Image 1). She underwent tumour resection, and histopathological workup was performed at WRH and London Health Sciences Centre (H&E Slide 1). Nine years later, she presented again with symptoms of elevated intracranial pressure and the imaging findings in Image 2. Tumour resection was performed (H&E Slide 2).

Discussion points

What are the major histological findings? In the first tumour? In the second tumour?
Differential diagnosis for each tumour?
What ancillary testing would be most informative of the diagnosis?

Image 1 (MRI 2017)

H&E Slide 1 (Tumour resection 2017)

Image 2 (MRI 2022, 2026)

H&E Slide 2 (Tumour resection 2026)